MANXDNA

Scope and Objectives
Up Manx Family Names Background DNA of the Isle of Man Scope and Objectives Scoreboard Sponsor a Name How to Take Part Results News about the Study

 

Objectives

  1. To provide a broad review of the Y-DNA profiles, by haplogroup and haplotype grouping, of male members of the main Manx families (as defined here)
  2. To compare the genetic origins of a Manx family name (learned via this study) with the earlier published origins of the name, deduced from the linguistic and historical research.
  3. Wherever possible, to identify genetic linkages between these individual Manx families and other families/tribes/clans outside the Isle of Man and the possible timeframes for such connections.
  4. To identify if there are any inter-relationships between the male lines of different Manx families, if they exist.
  5. To try and assess whether the level of genetic diversity on the Isle of Man is less than in the neighbouring areas of population, ie is there any evidence of a founder effect?

Scope

  1. The study is restricted to men bearing a family name belonging to the range of Manx families as defined here
  2. Using and coordinating existing Y-DNA results taken by Manx men as the basis for the main project database.
  3. New individuals wishing to participate should be prepared to pay for the cost of their own tests. No additional funds are available within the project at present, but the project coordinator will seek to obtain external funding if possible in time.
  4. Y-DNA data will be used as the principal indicator of Manx DNA but, if appropriate, mitochondrial DNA and autosomal DNA data may also be brought into consideration.

Project Stages and Timetable

Data Collection   

An ongoing process of data collection has already commenced to collate the Y-DNA results of Manx men around the world who have already taken a test. 
Members of families not yet covered will be targeted to seek their involvement in testing. At least 2 members of each Manx family grouping will be required to be tested in order to validate their results and exclude non-paternal events.
This means that a minimum of 200 men will need to be tested. In view of the sheer logistics of enrolling such participants and the financial resources required it is not expected that this process will be complete before mid 2013. Prioritisation of recruitment will be aimed at the larger families first.
Also possible comparator haplotypes from Ireland, Scotland and Scandinavia to be identified for comparison.  

See the Scoreboard for information on the latest progress

Analysis

The analysis and interpretation of the database will be a continuous process which will be refined over time as more and more data become available, not just from within the study, but also from other developments and analysis of the larger public Y-DNA databases worldwide.

Review of family name coverage and identification of major gaps 
Micro-analysis of individual name STR data by family 
Early clustering and TMRCA analysis  by family 
Further data collection as appropriate 
Macro-analysis across families 
Identification of any cross connections between families
Matching of Manx family DNA signatures against those in neighbouring Ireland, Scotland and England to try and identify earlier origins and connections.

Report and Publication 

Regular updates of progress will be published as appropriate on the study website

Preparation of a report on the outcome and conclusions of the Study to be published - By 2014

 

If you have any questions about this site please contact John A Creer Copyright John A Creer 2010-2017